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MYP_069378
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Basic Information
Met-enkephalin-Arg-Phe
Hormonal / Endocrine ▸ Hormone peptide
Neurological / Signaling ▸ Analgesic/opioid activity ▸ Analgesic
Neurological / Signaling ▸ Analgesic/opioid activity ▸ Opioid
Neurological / Signaling ▸ Analgesic/opioid activity ▸ opioid neuropeptide precursor family
Neurological / Signaling ▸ Neuromodulation
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide signaling
Neurological / Signaling ▸ Neuropeptide activity ▸ opioid neuropeptide precursor family
Neurological / Signaling ▸ Pain modulation ▸ Pronociceptive activity
Regulatory peptide ▸ Biological modulation
Regulatory peptide ▸ Biological regulation
Regulatory peptide ▸ Cell-cell communication
Regulatory peptide ▸ Cell signaling / Growth factor signaling ▸ Growth factor activity
Standard
7 amino acids
C42H56N10O9S
Standard
Sequence
YGGFMRF
Physicochemical Analysis
877.02 Da
8.75
0.76
0.55
0.1084
0.13
0.52
0.24
3.30
0.00
0.4286
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
320.05
-0.98
12.0
11.0
26.0
62.0
3.0
6.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0003278 VERIFIED: YES
Provenance & Taxonomy
Xenopus laevis [Animal]
Met-enkephalin-Arg-Phe
8355
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Analgesic Pronociceptive Neuropeptide Neuromodulator
Mammalian: 2.8 hour; Yeast: 10 min; E. coli: 2 min
PaperSource-linked PubMed record(s) for Met-enkephalin-Arg-Phe (Xenopus laevis): PMID 1721992 PMID1721992 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/1721992/
RECORD: Rec_0012792 VERIFIED: YES
Provenance & Taxonomy
Cavia porcellus [Animal]
Met-enkephalin-Arg-Phe
10141
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Analgesic Pronociceptive Neuropeptide Neuromodulator
Mammalian: 2.8 hour; Yeast: 10 min; E. coli: 2 min
PaperSource-linked PubMed record(s) for Met-enkephalin-Arg-Phe (Cavia porcellus): PMID 6316163 PMID6316163 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/6316163/
RECORD: Rec_0033344 VERIFIED: YES
Provenance & Taxonomy
Rattus norvegicus [Animal]
Opioid
10116
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Opioid Analgesic Neuromodulator
PMID20298575 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20298575/
RECORD: Rec_0046759 VERIFIED: YES
Provenance & Taxonomy
Mesocricetus auratus [Animal]
Opioid
10036
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Opioid Analgesic Neuromodulator
PMID20298575 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20298575/
RECORD: Rec_0054213 VERIFIED: YES
Provenance & Taxonomy
Mus musculus [Animal]
Opioid
10090
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Opioid Analgesic Neuromodulator
PMID20298575 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20298575/
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