Peptide Database

Peptide NameHepcidin antimicrobial peptide

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length89 amino acids

Chemical FormulaC428H680N118O123S14

DescriptionStandard

        MKAFSIAVAVTLVLAFICILESSAIPFTGVGELEEAGGNDTPVEAHQEMSMESWMMPKHVREKRQSHLSLCRYCCKCCKNKGCGFCCRF
    

Molecular Weight9895.60 Da

Isoelectric Point (pI)7.53

Net Charge (pH 7.0)0.69

Net Charge (pH 7.4) 0.17

Charge Density (pH 7.0) 0.0077

GRAVY Index0.12

Hydrophobic Moment 0.63

Boman Index0.08

Instability Index46.29

Aliphatic Index 71.24

Aromaticity 0.0787

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3833.89

LogP -36.59

H-bond Donors 142.0

H-bond Acceptors 141.0

Rotatable Bonds 330.0

Heavy Atoms 683.0

Ring Count 14.0

Amide Bonds 92.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0017687 VERIFIED: NO

Provenance & Taxonomy

OrganismCyprinodon variegatus [Bacterium]

FamilyHepcidin

Tax ID28743

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Non-hemolytic Non-ribosomal