Peptide Database

Peptide NameAlpha-defensin 6 (primates, mammals, animals)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Antimicrobial ▸ Antifungal

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length94 amino acids

Chemical FormulaC430H707N135O134S8

DescriptionStandard

        MRTLTILAAILLFALLAQAKSLQETADDAATQEQPGEDDQDLAVSFEENGLSTLRASGSQARRNCHCRIGHCRRPAAPMGVCIIHGQFGKLCCR
    

Molecular Weight10168.56 Da

Isoelectric Point (pI)6.80

Net Charge (pH 7.0)-0.28

Net Charge (pH 7.4) -0.75

Charge Density (pH 7.0) -0.0030

GRAVY Index-0.12

Hydrophobic Moment 0.56

Boman Index-0.02

Instability Index52.02

Aliphatic Index 86.38

Aromaticity 0.0319

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 375.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4339.64

LogP -51.02

H-bond Donors 156.0

H-bond Acceptors 145.0

Rotatable Bonds 342.0

Heavy Atoms 707.0

Ring Count 9.0

Amide Bonds 102.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0082919 VERIFIED: YES

Provenance & Taxonomy

OrganismMacaca mulatta [Animal]

FamilyDefensin

Tax ID9544

Structure & Mods

Configtopology not specified [Not included yet]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function