Peptide Database

Peptide NamevMIP-II

Function Ontology

Immunology ▸ Immune cell migration ▸ Chemotactic peptide

Immunology ▸ Immune modulation ▸ Immunomodulatory activity

Neurological / Signaling ▸ Receptor modulation ▸ Agonist

Neurological / Signaling ▸ Receptor modulation ▸ Antagonist

Neurological / Signaling ▸ Signaling peptide

Standard StatusStandard

Sequence Length70 amino acids

Chemical FormulaC359H577N101O94S5

DescriptionStandard

        LGASWHRPDKCCLGYQKRPLPQVLLSSWYPTSQLCSKPGVIFLTKRGRQVCADKSKDWVKKLMQQLPVTA
    

Molecular Weight7972.37 Da

Isoelectric Point (pI)9.90

Net Charge (pH 7.0)8.80

Net Charge (pH 7.4) 8.47

Charge Density (pH 7.0) 0.1257

GRAVY Index-0.39

Hydrophobic Moment 0.64

Boman Index-0.07

Instability Index37.87

Aliphatic Index 80.71

Aromaticity 0.0857

Extinction Coeff. Reduced 19480.00

Extinction Coeff. Oxidized 19730.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3143.26

LogP -27.84

H-bond Donors 113.0

H-bond Acceptors 109.0

Rotatable Bonds 260.0

Heavy Atoms 559.0

Ring Count 16.0

Amide Bonds 75.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0313909 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

FamilyGtoPdb peptide ligand

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Receptor antagonist Chemotactic Immunomodulatory Signaling peptide

TargetCCR1 (Human); CCR2 (Human); CCR5 (Human)