Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length78 amino acids

Chemical FormulaC395H615N109O107S10

DescriptionStandard

        MALNRKTFYFLFAMFFILVQLPSGCQAGLDFSQPFPSGEFAVCESCKLGRGKCRKECLENEKPDGNCRLNFLCCRQRI
    

Molecular Weight8923.42 Da

Isoelectric Point (pI)8.71

Net Charge (pH 7.0)3.43

Net Charge (pH 7.4) 3.08

Charge Density (pH 7.0) 0.0440

GRAVY Index-0.07

Hydrophobic Moment 0.46

Boman Index-0.01

Instability Index42.71

Aliphatic Index 67.56

Aromaticity 0.1282

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1990.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3497.56

LogP -32.07

H-bond Donors 127.0

H-bond Acceptors 121.0

Rotatable Bonds 297.0

Heavy Atoms 621.0

Ring Count 14.0

Amide Bonds 85.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0096143 VERIFIED: NO

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyDefensin

Tax ID9606

Structure & Mods

ConfigSingle-chain peptide backbone represented as a linear sequence entry [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial

RECORD: Rec_0098735 VERIFIED: NO