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MYP_069295
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Basic Information
Jelleine-1 [K3R;I4,6L;S5R;H7R]
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
8 amino acids
C50H87N17O9
Standard
Sequence
PFRLRLRL
Physicochemical Analysis
1070.33 Da
12.00
2.96
2.90
0.3698
-0.11
0.38
-0.39
80.97
146.25
0.1250
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
438.73
-1.61
18.0
12.0
35.0
76.0
2.0
7.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0206286 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Defensin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
hRBC: negligible hemolysis at 256 microM
256 μM
Hemolysis
PMID33878564 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33878564/
RECORD: Rec_0208858 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Defensin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Bacillus subtilis ATCC 23857
8 μM
MIC
PMID33878564 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33878564/
RECORD: Rec_0326923 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Defensin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
E. sakazakii ATCC 29544
32 μM
MIC
PMID33878564 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33878564/
RECORD: Rec_0384333 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Defensin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus epidermidis ATCC 12228
16 μM
MIC
PMID33878564 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33878564/
RECORD: Rec_0390891 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Defensin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus ATCC 29213
64 μM
MIC
PMID33878564 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33878564/
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