Peptide Database

Peptide NameColicin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length563 amino acids

Chemical FormulaC2778H4372N734O852S8

DescriptionStandard

        MIITRANVDQFPDLPEYVIRDIKQNGTVYNTTGGADEDGAFITDGGWVVNNGVDTLMVAAAKSDYFPWSKIPILADSDKDEYPSPNVGNGGSSPFNPNTKFTVNKPQKPVIISSNNNKLTNSSNNRELATNKGVMHFNGVVIEQLETFKKKYFLTKEAVNLVQDKLVESVISLYSKENSIDDNNVNSVKFMEFSEFDNNSFDELDLMSTIPAENLINNPDLMSGKLNEIAKNNGTVNVNARMAVIKENNKASAALVRTDGVLVTKEVPVYPANYIGNGYHMDIKNLGIEYALLPADSYSGLGLQGNIIQKYSNENKKFSYPEKVELPNKVENKRIEVPYPHQFNDAIIVFPRNSNLPPLYAYSGFPAIELKDKDPRPQQEQEFNEIKDSVKFTISFYEKATQEFGKKAAQLSRELAEQSKGKTIRNVEDALRTYEKYGQNINNKINAKDRAAIIKALESIDAKQLASNLGKFSKGLGYTNHAINAVELLVEFKNAVKTGNWRPFFVKAASITAGLASVALTAFAFSLIIGGPVGILGYALIIATVGALIDDALVEKVSGAIGI
    

Molecular Weight61941.36 Da

Isoelectric Point (pI)5.72

Net Charge (pH 7.0)-5.09

Net Charge (pH 7.4) -5.69

Charge Density (pH 7.0) -0.0090

GRAVY Index-0.31

Hydrophobic Moment 0.86

Boman Index0.03

Instability Index33.28

Aliphatic Index 89.04

Aromaticity 0.0888

Extinction Coeff. Reduced 47790.00

Extinction Coeff. Oxidized 47790.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0260077 VERIFIED: NO

Provenance & Taxonomy

OrganismProteus vulgaris [Bacterium]

FamilyColicin/Bacteriocin

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Anti-Gram-negative Non-hemolytic

TargetEscherichia coli (Gram-negative)

MethodQualitative functional evidence