Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length250 amino acids

Chemical FormulaC1267H1945N291O366S10

DescriptionStandard

        LSMLFVILGILPYLPPFTVPMPIDDLAEVDYSLNSLPAVFRQFIDLDLKGIVHPAGNFTGSHCVAAPFAIPDQSDSMLHLAFSEHFFQTSSFAYYTAGAFNITIAEETCSYFNISTEIFGSIIPEVAKYSVTPYPVMLKLMATEIPVISLEQDSFTVEIQGSMEVFAVLPDSTTQLLFTMNIAANTSIALNVFDQKLVGSLCLNRLQFSLAQSNVGFFEISLLENILSYILQTEVIPSANAKLSKGFPLP
    

Molecular Weight27430.38 Da

Isoelectric Point (pI)4.32

Net Charge (pH 7.0)-14.89

Net Charge (pH 7.4) -15.39

Charge Density (pH 7.0) -0.0595

GRAVY Index0.50

Hydrophobic Moment 0.62

Boman Index0.30

Instability Index45.86

Aliphatic Index 107.28

Aromaticity 0.1160

Extinction Coeff. Reduced 11920.00

Extinction Coeff. Oxidized 12045.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0161113 VERIFIED: NO

Provenance & Taxonomy

OrganismArenaria interpres (Ruddy turnstone) [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria