Peptide Database

Peptide NameGalanin-like peptide

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Hormonal / Endocrine ▸ Hormone peptide

Immunology ▸ Immune modulation ▸ Immunomodulatory activity

Neurological / Signaling ▸ Neuromodulation

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Regulatory peptide ▸ Biological modulation

Reproductive biology ▸ Reproductive modulation

Standard StatusStandard

Sequence Length60 amino acids

Chemical FormulaC291H464N86O83S

DescriptionStandard

        APAHRGRGGWTLNSAGYLLGPVLPVSSKADQGRKRDSALEILDLWKIIDGLPYSHSPRMT
    

Molecular Weight6527.39 Da

Isoelectric Point (pI)9.81

Net Charge (pH 7.0)2.97

Net Charge (pH 7.4) 2.67

Charge Density (pH 7.0) 0.0495

GRAVY Index-0.39

Hydrophobic Moment 0.52

Boman Index-0.01

Instability Index50.02

Aliphatic Index 89.50

Aromaticity 0.0667

Extinction Coeff. Reduced 13980.00

Extinction Coeff. Oxidized 13980.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2687.75

LogP -26.78

H-bond Donors 95.0

H-bond Acceptors 89.0

Rotatable Bonds 209.0

Heavy Atoms 461.0

Ring Count 13.0

Amide Bonds 61.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0112441 VERIFIED: NO

Provenance & Taxonomy

OrganismMus musculus [Animal]

FamilyGalanin-like peptide

Tax ID10090

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative Hormone Endocrine Neuropeptide Neuromodulator Reproductive regulator Receptor modulation Immunomodulatory

Half-LifeMammalian: 4.4 hour; Yeast: >20 hour; E. coli: >10 hour

RECORD: Rec_0233069 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide

Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/

RECORD: Rec_0297256 VERIFIED: NO

Provenance & Taxonomy

OrganismMus musculus [Animal]

FamilyGalanin

Tax ID10090

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide Neuromodulator