Peptide Database

Peptide NameCrustacean hyperglycemic hormone 3

Function Ontology

Developmental biology ▸ Molting regulation

Hormonal / Endocrine ▸ Hormone peptide

Neurological / Signaling ▸ Neuromodulation

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Regulatory peptide ▸ Biological regulation

Standard StatusStandard

Sequence Length72 amino acids

Chemical FormulaC368H555N101O111S6

DescriptionStandard

        ANFDPSCAGVYNRELLGRLSRLCDDCYNVFREPKVATECRNNCFYNPVFVQCLEYLIPADLHEEYQAHVQTV
    

Molecular Weight8362.34 Da

Isoelectric Point (pI)4.89

Net Charge (pH 7.0)-4.07

Net Charge (pH 7.4) -4.47

Charge Density (pH 7.0) -0.0566

GRAVY Index-0.28

Hydrophobic Moment 0.75

Boman Index-0.03

Instability Index45.46

Aliphatic Index 78.47

Aromaticity 0.1250

Extinction Coeff. Reduced 7450.00

Extinction Coeff. Oxidized 7825.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3430.02

LogP -32.28

H-bond Donors 121.0

H-bond Acceptors 115.0

Rotatable Bonds 265.0

Heavy Atoms 586.0

Ring Count 15.0

Amide Bonds 80.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0239080 VERIFIED: YES

Provenance & Taxonomy

OrganismPenaeus monodon [Animal]

FamilyCrustacean hyperglycemic hormone

Tax ID6687

Structure & Mods

Configdisulfide-constrained peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Disulfide7-43; 23-39; 26-52

Bio-Activity Profile

Function

Hormone Endocrine Neuropeptide Neuromodulator Metabolic regulation Physiological regulation Molting regulator

Targetthe sinus gland

Half-LifeMammalian: 4.4 hour; Yeast: >20 hour; E. coli: >10 hour

RECORD: Rec_0416938 VERIFIED: YES

Provenance & Taxonomy

OrganismPenaeus monodon [Animal]

FamilyCrustacean hyperglycemic hormone

Tax ID6687

Structure & Mods

Configdisulfide-constrained peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Disulfide7-43; 23-39; 26-52

Bio-Activity Profile

Function

Hormone Endocrine Neuropeptide Neuromodulator Metabolic regulation Physiological regulation Molting regulator

Half-LifeMammalian: 4.4 hour; Yeast: >20 hour; E. coli: >10 hour

RECORD: Rec_0421617 VERIFIED: NO

Provenance & Taxonomy

OrganismPenaeus monodon [Animal]

FamilyArthropod CHH/MIH/GIH/VIH hormone

Tax ID6687

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

Neuropeptide Arthropod neurohormone