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MYP_069181
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Basic Information
Phakellistatin 11
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
8 amino acids
C53H69N9O10
Standard
Sequence
QPFPFIFP
Physicochemical Analysis
992.17 Da
5.53
-0.24
-0.44
-0.0300
0.57
0.32
0.56
129.12
48.75
0.3750
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
283.74
1.35
7.0
10.0
23.0
72.0
6.0
8.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0335865 VERIFIED: YES
Provenance & Taxonomy
Phakellia sp. [Animal]
Phakellistatin
Structure & Mods
side-chain cyclized/stapled peptide [Cyclic]
mixed L/D or modified amino-acid peptide [Mixed]
None
None
f=D-Phe; i=D-Ile
Bio-Activity Profile
Antimicrobial Anticancer
SK-HEP-1
1.7 μM
IC50
PMID29893558 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29893558/
RECORD: Rec_0345598 VERIFIED: YES
Provenance & Taxonomy
Phakellia sp. [Animal]
Phakellistatin
Structure & Mods
side-chain cyclized/stapled peptide [Cyclic]
mixed L/D or modified amino-acid peptide [Mixed]
None
None
f=D-Phe; i=D-Ile
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
PMID29893558 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29893558/
RECORD: Rec_0361878 VERIFIED: YES
Provenance & Taxonomy
Phakellia sp. [Animal]
Phakellistatin
Structure & Mods
side-chain cyclized/stapled peptide [Cyclic]
mixed L/D or modified amino-acid peptide [Mixed]
None
None
f=D-Phe; i=D-Ile
Bio-Activity Profile
Antimicrobial Anticancer
MDA-MB-231
3.2 μM
IC50
PMID29893558 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29893558/
RECORD: Rec_0395141 VERIFIED: YES
Provenance & Taxonomy
Phakellia sp. [Animal]
Phakellistatin
Structure & Mods
side-chain cyclized/stapled peptide [Cyclic]
mixed L/D or modified amino-acid peptide [Mixed]
None
None
f=D-Phe; i=D-Ile
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
PMID29893558 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29893558/
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