Peptide Database

Peptide NameHPV-31 L1 Cta

Function Ontology

Antimicrobial

Antiviral

Antiviral ▸ Anti-HPV

Antiviral ▸ Antiviral mechanism ▸ Viral entry inhibition

Antiviral ▸ Antiviral mechanism ▸ Viral entry inhibition ▸ Entry inhibitor

Enzyme modulation ▸ Enzyme inhibition ▸ Infection inhibition

Standard StatusStandard

Sequence Length13 amino acids

Chemical FormulaC69H115N25O15

DescriptionStandard

        GYRARPKFKAGKR
    

Molecular Weight1534.81 Da

Isoelectric Point (pI)11.74

Net Charge (pH 7.0)5.76

Net Charge (pH 7.4) 5.55

Charge Density (pH 7.0) 0.4428

GRAVY Index-1.73

Hydrophobic Moment 0.48

Boman Index-0.64

Instability Index11.49

Aliphatic Index 15.38

Aromaticity 0.1538

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 687.72

LogP -6.61

H-bond Donors 26.0

H-bond Acceptors 21.0

Rotatable Bonds 52.0

Heavy Atoms 109.0

Ring Count 3.0

Amide Bonds 12.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0277856 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide; DSSP H 0.0%, E 0.0%, T 30.8%, C 69.2% [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Antiviral Antimicrobial

RECORD: Rec_0281303 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilySynthetic peptide

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Antiviral Infection inhibition

TargetInhibition of pseudovirions infection

Activity6.515 μM

Method% inhibition

Half-LifeMammalian: 30 h; Yeast: >20 h; E. coli: >10 h

PaperPositively charged synthetic peptides from structural proteins of papillomaviruses abrogate human papillomavirus infectivity. | Bousarghin L, Touzé A, Yvonnet B, Coursaget P. | J Med Virol. 2004 Jul;73(3):474-80. | DOI:10.1002/jmv.20114 | PMID:15170645 PMID15170645 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15170645/

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