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MYP_069124
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Basic Information
Brevinin-2GHk (1-25)[L14R]
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
25 amino acids
C121H197N35O32
Standard
Sequence
GFSSLFKAGAKYLRKQVGKAGAQQL
Physicochemical Analysis
2654.07 Da
10.58
4.76
4.54
0.1902
-0.27
0.74
-0.01
19.56
74.40
0.1200
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1117.66
-11.57
39.0
37.0
93.0
188.0
3.0
27.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0296976 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Brevinin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Staphylococcus aureus NCTC 12493
64 μM
MIC
PMID32075067 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32075067/
RECORD: Rec_0300061 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Brevinin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Klebsiella pneumoniae ATCC 43816
128 μM
MIC
PMID32075067 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32075067/
RECORD: Rec_0346382 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Brevinin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Staphylococcus aureus NCTC 10788
32 μM
MBC
PMID32075067 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32075067/
RECORD: Rec_0350444 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Brevinin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Cytotoxic
Human microvascular endothelial cells HMEC-1
100 μM
Cytotoxicity
PMID32075067 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32075067/
RECORD: Rec_0380667 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Brevinin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Candida albicans NCYC 1467
64 μM
MIC
PMID32075067 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32075067/
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