Peptide Database

Peptide NameCaerin-1.7 [Cleaved into: Caerin-1.7.1]

Function Ontology

Anticancer

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antiviral

Antiviral ▸ Anti-HIV

Antiviral ▸ Antiviral mechanism ▸ Viral release inhibition

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length25 amino acids

Chemical FormulaC126H210N32O29

DescriptionStandard

        GLFKVLGSVAKHLLPHVAPVIAEKL
    

Molecular Weight2637.21 Da

Isoelectric Point (pI)9.70

Net Charge (pH 7.0)1.93

Net Charge (pH 7.4) 1.62

Charge Density (pH 7.0) 0.0774

GRAVY Index0.88

Hydrophobic Moment 0.59

Boman Index0.36

Instability Index19.91

Aliphatic Index 152.00

Aromaticity 0.0400

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 937.09

LogP -3.31

H-bond Donors 31.0

H-bond Acceptors 33.0

Rotatable Bonds 85.0

Heavy Atoms 187.0

Ring Count 5.0

Amide Bonds 24.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0394441 VERIFIED: YES

Provenance & Taxonomy

OrganismLitoria xanthomera [Animal]

FamilyCaerin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative

TargetStaphylococcus aureus ATCC 29123

Activity12-50 μg/mL

MethodMIC

RECORD: Rec_0406854 VERIFIED: YES

Provenance & Taxonomy

OrganismLitoria xanthomera [Animal]

FamilyCaerin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermAmidation

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antiviral

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