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MYP_069122
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Basic Information
Caerin-1.7 [Cleaved into: Caerin-1.7.1]
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antiviral
Antiviral ▸ Anti-HIV
Antiviral ▸ Antiviral mechanism ▸ Viral release inhibition
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
25 amino acids
C126H210N32O29
Standard
Sequence
GLFKVLGSVAKHLLPHVAPVIAEKL
Physicochemical Analysis
2637.21 Da
9.70
1.93
1.62
0.0774
0.88
0.59
0.36
19.91
152.00
0.0400
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
937.09
-3.31
31.0
33.0
85.0
187.0
5.0
24.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0137942 VERIFIED: YES
Provenance & Taxonomy
Litoria xanthomera [Animal]
Caerin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Bacillus cereus
100 μg/mL
MIC
PMID15203252 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15203252/
RECORD: Rec_0153529 VERIFIED: YES
Provenance & Taxonomy
Litoria xanthomera [Animal]
Caerin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Streptococcus uberis
50 μg/mL
MIC
PMID15203252 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15203252/
RECORD: Rec_0155324 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct based on Litoria xanthomera [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antiviral Anticancer
Micrococcus luteus
12.5 μg/mL
MIC
PaperNew caerin antibacterial peptides from the skin glands of the Australian tree frog Litoria xanthomera.
RECORD: Rec_0170764 VERIFIED: YES
Provenance & Taxonomy
Litoria xanthomera [Animal]
Caerin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Pasteuretla multocida
25 μg/mL
MIC
PMID15203252 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15203252/
RECORD: Rec_0171818 VERIFIED: YES
Provenance & Taxonomy
Litoria xanthomera [Animal]
Caerin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Micrococcus luteus
12 μg/mL
MIC
PMID15203252 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15203252/
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