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MYP_069094
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Basic Information
PENK(114-133)
Neurological / Signaling ▸ Analgesic/opioid activity ▸ Analgesic
Neurological / Signaling ▸ Analgesic/opioid activity ▸ Opioid
Neurological / Signaling ▸ Neuromodulation
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide
Neurological / Signaling ▸ Pain modulation ▸ Pronociceptive activity
Regulatory peptide ▸ Biological modulation
Regulatory peptide ▸ Biological regulation
Standard
20 amino acids
C95H145N21O37S
Standard
Sequence
MDELYPVEPEEEANGGEILA
Physicochemical Analysis
2205.35 Da
4.05
-7.48
-7.71
-0.3741
-0.57
0.21
0.09
90.36
83.00
0.0500
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
923.06
-7.04
28.0
31.0
71.0
154.0
3.0
20.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0027745 VERIFIED: YES
Provenance & Taxonomy
Rattus norvegicus [Animal]
PENK(114-133)
10116
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Analgesic Pronociceptive Neuropeptide Neuromodulator Growth regulation Development regulation Receptor modulation
Mammalian: 30 hour; Yeast: >20 hour; E. coli: >10 hour
PaperSource-linked PubMed record(s) for PENK(114-133) (Rattus norvegicus): PMID 19164277 PMID19164277 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19164277/
RECORD: Rec_0159737 VERIFIED: YES
Provenance & Taxonomy
Mesocricetus auratus [Animal]
Opioid
10036
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Opioid Analgesic Neuromodulator
PMID19164277 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19164277/
RECORD: Rec_0253519 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Neuropeptide
Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/
RECORD: Rec_0385452 VERIFIED: YES
Provenance & Taxonomy
Rattus norvegicus [Animal]
Opioid
10116
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Opioid Analgesic Neuromodulator
PMID19164277 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19164277/