MYP_069080
Exendin-4
Antimicrobial
Binding / Molecular interaction
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Binding activity
Cardiovascular
Delivery / Targeting
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Barrier transport
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Blood-brain barrier shuttle
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Blood-Brain Barrier
Delivery / Targeting
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Drug delivery vehicle
Hormonal / Endocrine
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Hormone peptide
Metabolic
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Appetite and feeding regulation
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Metabolic
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Glucose metabolism
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Metabolic
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Glucose metabolism
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Antidiabetic
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Metabolic
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Glucose metabolism
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Antidiabetic
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Regulatory peptide
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Biological regulation
Venom / Toxin
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General toxin
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Toxin
Venom / Toxin
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Toxin
Standard
39 amino acids
C184H281N49O61S
Standard
HGEGTFTSDLSKQMEEEAVRLFIEWLKNGGPSSGAPPPS
4187.56 Da
4.70
-3.14
-3.40
-0.0805
-0.69
0.71
0.01
64.08
52.56
0.0769
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Amino Acid Composition
1743.96
-20.00
58.0
60.0
134.0
295.0
9.0
40.0
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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RECORD: Rec_0029737
VERIFIED: YES
Provenance & Taxonomy
Heloderma suspectum [Animal]
glucagon family
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Toxin
Venom
glucagon family
RECORD: Rec_0030405
VERIFIED: NO
Provenance & Taxonomy
Homo sapiens [Animal]
Insulin
9606
Structure & Mods
linear peptide/protein therapeutic [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Hormone replacement
Mean terminal half-life is 2.4 hours.
RECORD: Rec_0033536
VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Exendin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Glucose-dependent insulin secretion
Glucagon secretion suppression
Gastric emptying delay
Radioimmunoassay
Monkey (Subcutaneous injection), in vivo; 278640 s
RECORD: Rec_0041224
VERIFIED: NO
Provenance & Taxonomy
Heloderma suspectum [Animal]
8554
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Bio-Activity Profile
-
RECORD: Rec_0041875
VERIFIED: YES
Provenance & Taxonomy
Heloderma horridum [Animal]
Exendin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Fusion of Alpha-1 Antitrypsin Monovariant [α1AT(P357N)]
Bio-Activity Profile
Insulinotropic
~10000 μM
EIA
Rat plasma (Subcutaneous), in vivo; 68760 s
Showing 5 records on this page · Page 1 of 8