Peptide Database

Peptide NameBeta-defensin 1TB

Function Ontology

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Standard StatusStandard

Sequence Length36 amino acids

Chemical FormulaC168H253N45O51S6

DescriptionStandard

        DHYNCYKSGGTCLYSSCPIFTKATGTCYLGKGHCCK
    

Molecular Weight3911.47 Da

Isoelectric Point (pI)8.62

Net Charge (pH 7.0)2.87

Net Charge (pH 7.4) 2.46

Charge Density (pH 7.0) 0.0797

GRAVY Index-0.31

Hydrophobic Moment 0.35

Boman Index0.04

Instability Index37.87

Aliphatic Index 35.28

Aromaticity 0.1389

Extinction Coeff. Reduced 5960.00

Extinction Coeff. Oxidized 6335.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1537.39

LogP -18.90

H-bond Donors 61.0

H-bond Acceptors 62.0

Rotatable Bonds 123.0

Heavy Atoms 270.0

Ring Count 8.0

Amide Bonds 36.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0028787 VERIFIED: YES

Provenance & Taxonomy

OrganismMicrocebus murinus [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

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TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)