Peptide Database

Peptide Nameneutrophil defensin 1

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Antimicrobial ▸ Antifungal

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length148 amino acids

Chemical FormulaC691H1109N197O212S10

DescriptionStandard

        MKVPDSPVTTNTNKAWDRGLLSALSSHPPSPRISLETQLTPHSTHSPPAPPAPGDPSMKTLALLAALLLLALQAQAGPLQERDEEMPLQELPVAEDRDVSISITWNENSIPQAPVRSMACACRRPACLAGETRLGTCHFGNNVFVFCC
    

Molecular Weight15889.04 Da

Isoelectric Point (pI)5.74

Net Charge (pH 7.0)-3.18

Net Charge (pH 7.4) -3.71

Charge Density (pH 7.0) -0.0215

GRAVY Index-0.18

Hydrophobic Moment 0.65

Boman Index0.04

Instability Index72.43

Aliphatic Index 82.50

Aromaticity 0.0338

Extinction Coeff. Reduced 11000.00

Extinction Coeff. Oxidized 11375.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6406.93

LogP -72.07

H-bond Donors 219.0

H-bond Acceptors 223.0

Rotatable Bonds 497.0

Heavy Atoms 1110.0

Ring Count 29.0

Amide Bonds 159.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0187506 VERIFIED: NO

Provenance & Taxonomy

OrganismMicrocebus murinus [Animal]

FamilyDefensin

Tax ID30608

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Antifungal Non-hemolytic Non-ribosomal