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MYP_068998
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Basic Information
Granulysin F2
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Mycobacterium
Delivery / Targeting ▸ Targeting ligand ▸ Targeting
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
23 amino acids
C123H202N50O32S3
Standard
Sequence
VCRTGRSRWRDVCRNFMRRYQSR
Physicochemical Analysis
2989.43 Da
11.78
6.71
6.47
0.2919
-1.45
0.86
-0.74
102.91
25.22
0.1304
6990.00
7115.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1418.91
-17.38
58.0
42.0
100.0
208.0
4.0
24.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0042299 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Escherichia coli D21 LC
23 μM
PMID28314993;10585872 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28314993/
RECORD: Rec_0055209 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus aureus Cowan 1 LC
300 μM
PMID28314993;10585872 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28314993/
RECORD: Rec_0091012 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
human red blood cells
300 μM
Hemolysis
PMID28314993;10585872 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28314993/
RECORD: Rec_0136796 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Streptococcus pneumoniae ATCC 49619
100 μM
MIC
PMID28314993;10585872 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28314993/
RECORD: Rec_0147284 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Source entry describes small-molecule/peptide conjugation at one terminus; exact terminus not explicitly assigned in source metadata
Conjugate type: amide; Conjugated small molecule: coumarone derivative TB5, antitubercular drug
Bio-Activity Profile
Antimicrobial Targeting
PaperEnhanced Cellular Uptake of a New, in Silico Identified Antitubercular Candidate by Peptide Conjugation Evidence URLhttps://doi.org/10.1021/bc200221t
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