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MYP_068922
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Basic Information
Anal 5 (antimicrobial peptide HP (2-20)analogue)
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
19 amino acids
C101H178N30O28
Standard
Sequence
AKKVSKRLEKLFSKIQNDK
Physicochemical Analysis
2260.68 Da
10.30
4.79
4.59
0.2523
-1.19
0.78
-0.46
8.76
82.11
0.0526
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1006.38
-9.32
35.0
33.0
86.0
159.0
1.0
20.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0171320 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
S. cerevisiae
25 μM
MIC
PMID16255716 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16255716/
RECORD: Rec_0186185 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
B. cinerea
50 μM
MIC
PMID16255716 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16255716/
RECORD: Rec_0195818 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Saccharomyces cerevisiae
25 μg/mL
MIC
PaperInteractions between the plasma membrane and the antimicrobial peptide HP (2-20) and its analogues derived from Helicobacter pylori. Biochem J. 2006 Feb 15;394(Pt 1):105-114. doi: 10.1042/BJ20051574. PMID: 16255716. PMID16255716 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16255716/
RECORD: Rec_0202871 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anticancer Toxic Hemolytic
PaperHemolytik: a database of experimentally determined hemolytic and non-hemolytic peptides PMID24174543 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24174543/
RECORD: Rec_0205519 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
T. beigelii
12.5 μM
MIC
PMID16255716 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16255716/
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