Peptide Database

Peptide NameBovine Beta-defensin 2

Function Ontology

—

Standard StatusStandard

Sequence Length40 amino acids

Chemical FormulaC195H316N66O46S7

DescriptionStandard

        ISGPLSCHRKRGVCFPIRCPGHMRQIGTCFGRPIKCCRSW
    

Molecular Weight4545.46 Da

Isoelectric Point (pI)10.22

Net Charge (pH 7.0)7.87

Net Charge (pH 7.4) 7.48

Charge Density (pH 7.0) 0.1968

GRAVY Index-0.21

Hydrophobic Moment 0.71

Boman Index-0.11

Instability Index56.19

Aliphatic Index 56.00

Aromaticity 0.0750

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5875.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1783.66

LogP -18.69

H-bond Donors 71.0

H-bond Acceptors 63.0

Rotatable Bonds 144.0

Heavy Atoms 314.0

Ring Count 10.0

Amide Bonds 40.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0275736 VERIFIED: YES

Provenance & Taxonomy

OrganismBubalus bubalis [Animal]

FamilyDefensin

Structure & Mods

ConfigDNA-encoded linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

-

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)