Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length361 amino acids

Chemical FormulaC1802H2839N491O522S6

DescriptionStandard

        MAILEKELAQLKLPDISGDSRVLRVGKVRYELSRLRLRDFHLPYSRITPISNVGLQVSISNAFAELDGDWRVKFLFIRSSGSFNLKVENVYIKITLSLGSDTTGKPTISTSDCSASISEVRVLFSGKLGWLYNLFHSVIESRLRKILESKVCDNVAKSVHNELQTYLQTLPVTAKIDGKTGIDYSLVASPRATAQSVDADLKGEFYSLAHHSTVPFPPLPLAFPSDHDRMVYFGASSYFFNTAGIAYHEAGALVFEITDAMVSGTSGTGLGKRFHLARCSRSSVGEAPTGNVSAVINVRSGRIVGSLDVGRYRGEQPLTGQEWLGVFLFWVPRDREARLDEGFPLPLLDRIQLSNILVKFY
    

Molecular Weight39926.18 Da

Isoelectric Point (pI)8.99

Net Charge (pH 7.0)5.21

Net Charge (pH 7.4) 4.46

Charge Density (pH 7.0) 0.0144

GRAVY Index-0.03

Hydrophobic Moment 0.64

Boman Index0.06

Instability Index31.78

Aliphatic Index 97.45

Aromaticity 0.0970

Extinction Coeff. Reduced 39880.00

Extinction Coeff. Oxidized 40005.00

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Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0198904 VERIFIED: NO

Provenance & Taxonomy

OrganismLamprotornis superbus [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria