Peptide Database

Peptide NameBeta-defensin125

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length137 amino acids

Chemical FormulaC671H1052N180O219S10

DescriptionStandard

        SFEPQKCWKNNIGHCRRRCLDTERYILLCRNKLSCCISIIISHEYTRRPAFPVIHLEDITFDYSDVDSFTGSPVSMLNDLITFDTTKFGETITPETNTPETTMPPSETTSSKTTMPPSETATSETMPPPSQTALTHN
    

Molecular Weight15465.26 Da

Isoelectric Point (pI)5.28

Net Charge (pH 7.0)-5.22

Net Charge (pH 7.4) -5.75

Charge Density (pH 7.0) -0.0381

GRAVY Index-0.52

Hydrophobic Moment 0.60

Boman Index-0.05

Instability Index79.79

Aliphatic Index 59.78

Aromaticity 0.0730

Extinction Coeff. Reduced 9970.00

Extinction Coeff. Oxidized 10345.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6368.35

LogP -75.35

H-bond Donors 226.0

H-bond Acceptors 228.0

Rotatable Bonds 491.0

Heavy Atoms 1080.0

Ring Count 28.0

Amide Bonds 144.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0207923 VERIFIED: NO

Provenance & Taxonomy

OrganismPongo pygmaeus [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial