Peptide Database

Peptide NamePro-thyrotropin-releasing hormone

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Standard StatusStandard

Sequence Length232 amino acids

Chemical FormulaC1162H1809N357O357S4

DescriptionStandard

        LLEAAQEEGAVTPDLPGLEKVQVRPERRFLRKDLQRVRGDLGAALDSWITKRQHPGKREEKEEDVEAEERGDLGEVGAWRPHKRQHPGRRANQDKDSWSDEGDSDWLPPSWLPDFFLDSWFSDAPQVKRQHPGRRSFPWMESDVTKRQHPGRRFIDPELQRSWEETEGEEGGLMPEKRQHPGKRAVGHPCGPQGICGQTGLLQLLGDLSRGQETLAKQTPQLEAWVREPLEE
    

Molecular Weight26620.23 Da

Isoelectric Point (pI)5.52

Net Charge (pH 7.0)-7.56

Net Charge (pH 7.4) -8.23

Charge Density (pH 7.0) -0.0326

GRAVY Index-1.17

Hydrophobic Moment 0.80

Boman Index-0.25

Instability Index71.07

Aliphatic Index 59.70

Aromaticity 0.0647

Extinction Coeff. Reduced 49500.00

Extinction Coeff. Oxidized 49625.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0016401 VERIFIED: NO

Provenance & Taxonomy

OrganismMus musculus [Animal]

FamilyTRH

Tax ID10090

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Other ModsPro55 Amidation; Pro87 Amidation; Gln130 Pyroglutamylation; Pro132 Amidation; Gln148 Pyroglutamylation; Pro150 Amidation; Pro181 Amidation

Bio-Activity Profile

Function

Hormone Neuropeptide