Peptide Database

Peptide NameT622

Function Ontology

Antimicrobial

Antiviral

Antiviral ▸ Antiviral mechanism ▸ Viral fusion inhibition ▸ Fusion inhibitor

Standard StatusStandard

Sequence Length35 amino acids

Chemical FormulaC181H286N48O64

DescriptionStandard

        INNYTSLIHSLIEESQNQQEKNEQELLELDKWASL
    

Molecular Weight4158.49 Da

Isoelectric Point (pI)4.30

Net Charge (pH 7.0)-5.14

Net Charge (pH 7.4) -5.41

Charge Density (pH 7.0) -0.1468

GRAVY Index-0.90

Hydrophobic Moment 0.47

Boman Index-0.11

Instability Index56.83

Aliphatic Index 103.14

Aromaticity 0.0571

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 6990.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1876.43

LogP -19.21

H-bond Donors 61.0

H-bond Acceptors 60.0

Rotatable Bonds 146.0

Heavy Atoms 293.0

Ring Count 4.0

Amide Bonds 42.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0050300 VERIFIED: YES

Provenance & Taxonomy

OrganismHuman immunodeficiency virus 1 [Virus]

Tax ID11676

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antiviral Fusion inhibitor

TargetCEM

Activity0.23 μg/mL

MethodIC50

RECORD: Rec_0141331 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Antimicrobial Antiviral