Peptide Database

Peptide NameInsulin-1 A chain

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Regulatory peptide ▸ Biological regulation

Standard StatusStandard

Sequence Length22 amino acids

Chemical FormulaC104H157N27O36S4

DescriptionStandard

        VGIVEQCCHSPCSLYDLENYCN
    

Molecular Weight2489.78 Da

Isoelectric Point (pI)4.13

Net Charge (pH 7.0)-3.21

Net Charge (pH 7.4) -3.54

Charge Density (pH 7.0) -0.1461

GRAVY Index0.00

Hydrophobic Moment 0.33

Boman Index0.11

Instability Index45.42

Aliphatic Index 79.55

Aromaticity 0.0909

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3230.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1016.40

LogP -11.05

H-bond Donors 37.0

H-bond Acceptors 38.0

Rotatable Bonds 77.0

Heavy Atoms 171.0

Ring Count 4.0

Amide Bonds 24.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0416801 VERIFIED: YES

Provenance & Taxonomy

OrganismHuso dauricus [Animal]

FamilyInsulin

Tax ID55293

Structure & Mods

Configdisulfide-constrained peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide7-12

Bio-Activity Profile

Function

Hormone Endocrine Metabolic regulation Physiological regulation

Half-LifeMammalian: 100 hour; Yeast: >20 hour; E. coli: >10 hour