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MYP_068782
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Basic Information
Brevinin-1GHd, Brevinin-1HL
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Immunology ▸ Inflammation modulation ▸ Anti-inflammatory
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
24 amino acids
C116H196N28O28S2
Standard
Sequence
FLGALFKVASKLVPAAICSISKKC
Physicochemical Analysis
2495.10 Da
9.70
3.74
3.50
0.1557
1.11
0.53
0.32
8.76
122.08
0.0833
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
888.60
-5.85
33.0
34.0
83.0
174.0
3.0
23.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0380397 VERIFIED: YES
Provenance & Taxonomy
Sylvirana guentheri,Hylarana latouchii [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Escherichia coli NCTC 10418
8 μM
MIC
PMID32347293 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32347293/
RECORD: Rec_0383312 VERIFIED: YES
Provenance & Taxonomy
Sylvirana guentheri,Hylarana latouchii [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Chromobacterium violaceum ATCC 12472
205.2 μM
MIC
PMID32347293 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32347293/
RECORD: Rec_0387378 VERIFIED: YES
Provenance & Taxonomy
Sylvirana guentheri [Animal]
Brevinin
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
Disulfide bond(s) reported
Free
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Cytotoxic
PMID32347293 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32347293/
RECORD: Rec_0390046 VERIFIED: YES
Provenance & Taxonomy
Sylvirana guentheri,Hylarana latouchii [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Enterococcus faecalis NCTC 12697
12.8 μM
MIC
PMID32347293 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32347293/
RECORD: Rec_0407035 VERIFIED: YES
Provenance & Taxonomy
Sylvirana guentheri [Animal]
Brevinin
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
Disulfide bond(s) reported
Free
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
albicans
4 μM
MIC
PMID32347293 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32347293/
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