MYP_068782
Brevinin-1GHd, Brevinin-1HL
Anticancer
Anticancer
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Cytotoxic anticancer activity
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Cytotoxic
Antimicrobial
Antimicrobial
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Antibacterial
Antimicrobial
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Antibacterial
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Anti-Gram-negative
Antimicrobial
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Antibacterial
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Anti-Gram-positive
Antimicrobial
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Antifungal
Immunology
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Inflammation modulation
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Anti-inflammatory
Toxicity / Safety
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Blood cell toxicity
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Hemolysis
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Hemolytic
Toxicity / Safety
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Cytotoxicity
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Cytotoxic
Venom / Toxin
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General toxin
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Cytotoxic
Standard
24 amino acids
C116H196N28O28S2
Standard
FLGALFKVASKLVPAAICSISKKC
2495.10 Da
9.70
3.74
3.50
0.1557
1.11
0.53
0.32
8.76
122.08
0.0833
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Amino Acid Composition
888.60
-5.85
33.0
34.0
83.0
174.0
3.0
23.0
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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RECORD: Rec_0243404
VERIFIED: YES
Provenance & Taxonomy
Sylvirana guentheri [Animal]
Brevinin
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
Disulfide bond(s) reported
Free
Bio-Activity Profile
Antimicrobial
Antibacterial
Anti-Gram-positive
Anti-Gram-negative
MRSA
4 μM
MIC
RECORD: Rec_0248501
VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Anticancer
RECORD: Rec_0261414
VERIFIED: YES
Provenance & Taxonomy
Hoplobatrachus rugulosus [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
18-24
Bio-Activity Profile
Antimicrobial
Antifungal
Anticancer
Anti-inflammatory
Staphylococcus aureus or MRSA
2-4 μM
MIC
RECORD: Rec_0295795
VERIFIED: YES
Provenance & Taxonomy
Sylvirana guentheri,Hylarana latouchii [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Antibacterial
Antifungal
Staphylococcus aureus NCTC 10788
2 μM
MIC
RECORD: Rec_0312607
VERIFIED: YES
Provenance & Taxonomy
Sylvirana guentheri [Animal]
Brevinin
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
Disulfide bond(s) reported
Free
Bio-Activity Profile
Antimicrobial
Antibacterial
Anti-Gram-positive
Anti-Gram-negative
Pseudomonas aeruginosa
32 μM
MIC
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