Peptide Database

Peptide NameDPV6

Function Ontology

Anticancer

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Delivery / Targeting ▸ Cell penetration ▸ Cell-penetrating peptide

Delivery / Targeting ▸ Drug delivery vehicle

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length17 amino acids

Chemical FormulaC88H165N37O21

DescriptionStandard

        GRPRESGKKRKRKRLKP
    

Molecular Weight2077.49 Da

Isoelectric Point (pI)12.00

Net Charge (pH 7.0)8.76

Net Charge (pH 7.4) 8.55

Charge Density (pH 7.0) 0.5152

GRAVY Index-2.74

Hydrophobic Moment 0.34

Boman Index-1.11

Instability Index70.74

Aliphatic Index 22.94

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1008.47

LogP -11.71

H-bond Donors 38.0

H-bond Acceptors 30.0

Rotatable Bonds 77.0

Heavy Atoms 146.0

Ring Count 2.0

Amide Bonds 16.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0012369 VERIFIED: YES

Provenance & Taxonomy

OrganismProtein derived [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermCys addition

C-TermNone

Bio-Activity Profile

Function

Antimicrobial Anticancer Cytotoxic

RECORD: Rec_0037530 VERIFIED: YES

Provenance & Taxonomy

OrganismProtein derived [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermCys addition

C-TermNone

Bio-Activity Profile

Function

Antimicrobial Anticancer Hemolytic

RECORD: Rec_0067876 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyDPV/CAP37-derived

Tax ID9606

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermCys addition for conjugation

C-TermNone

Other ModsN-term detail: Cys added to N -terminus for conjugation of report

Bio-Activity Profile

Function

Cell-penetrating peptide

TargetHeLa; HCT116; HL-60; K562; Molt4; NIH-3T3; primary hepatocyte cultures

MethodCellular uptake assay

RECORD: Rec_0184530 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyDPV

Tax ID9606

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermCysteine addition

C-TermNone

Bio-Activity Profile

Function

Cell-penetrating peptide Cargo delivery

RECORD: Rec_0384400 VERIFIED: YES

Provenance & Taxonomy

OrganismProtein derived [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermCys addition

C-TermNone

Bio-Activity Profile

Function

Antimicrobial Anticancer

TargetNot available