Peptide Database

Peptide NameNeurophysin 2

Function Ontology

Cardiovascular ▸ Vascular tone modulation ▸ Vasoactive peptide

Cardiovascular ▸ Vascular tone modulation ▸ Vasoconstrictor activity

Hormonal / Endocrine ▸ Hormone peptide

Neurological / Signaling ▸ Neuromodulation

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Regulatory peptide ▸ Biological modulation

Standard StatusStandard

Sequence Length95 amino acids

Chemical FormulaC402H644N124O136S15

DescriptionStandard

        AMSDLELRQCLPCGPGGKGRCFGPSICCGDELGCFVGTAEALRCQEENYLPSPCQSGQKPCGSGGRCAAAGICCNDESCVTEPECREGASFLRRA
    

Molecular Weight9871.14 Da

Isoelectric Point (pI)4.85

Net Charge (pH 7.0)-3.32

Net Charge (pH 7.4) -3.73

Charge Density (pH 7.0) -0.0349

GRAVY Index-0.25

Hydrophobic Moment 0.77

Boman Index-0.03

Instability Index59.47

Aliphatic Index 51.47

Aromaticity 0.0421

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 2365.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4130.97

LogP -56.49

H-bond Donors 154.0

H-bond Acceptors 148.0

Rotatable Bonds 321.0

Heavy Atoms 677.0

Ring Count 11.0

Amide Bonds 100.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0168899 VERIFIED: YES

Provenance & Taxonomy

OrganismSus scrofa [Animal]

FamilyNeurophysin

Tax ID9823

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide10-54; 13-27; 21-44; 28-34; 61-73; 67-85; 74-79

Bio-Activity Profile

Function

Hormone Endocrine Neuropeptide Neuromodulator Vasoactive Vasoconstrictor Receptor modulation

Half-LifeMammalian: 4.4 hour; Yeast: >20 hour; E. coli: >10 hour

RECORD: Rec_0308794 VERIFIED: YES