Peptide Database

Peptide Namebeta-Defensin-3

Function Ontology

Antimicrobial

Standard StatusStandard

Sequence Length45 amino acids

Chemical FormulaC219H381N75O57S7

DescriptionStandard

        GIINTLQKYYCRVRGGRCAVLSCLPKEEQIGKCPMRGRKCCRRKK
    

Molecular Weight5201.29 Da

Isoelectric Point (pI)10.08

Net Charge (pH 7.0)10.70

Net Charge (pH 7.4) 10.39

Charge Density (pH 7.0) 0.2377

GRAVY Index-0.66

Hydrophobic Moment 0.63

Boman Index-0.34

Instability Index54.06

Aliphatic Index 67.11

Aromaticity 0.0444

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2200.35

LogP -23.14

H-bond Donors 86.0

H-bond Acceptors 75.0

Rotatable Bonds 182.0

Heavy Atoms 358.0

Ring Count 4.0

Amide Bonds 47.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0402620 VERIFIED: NO

Provenance & Taxonomy

OrganismHylobates lar [Animal]; Hylobates moloch [Animal]

FamilyDefensin

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide11-40; 18-33; 23-41

Bio-Activity Profile

Function

Antimicrobial