Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length426 amino acids

Chemical FormulaC2148H3339N537O597S19

DescriptionStandard

        MFQLIIIVVLTIVSCTTGENPAFQVTLNNKGLQYGKHVAAGWIQDRLGLITLPDISGEALLVHYTLSGIKITKCDFPEPSVEFYQNVTGLKSSITGLSIAVNGSWATHLGVIHDGGTFDLAVFNVGVTSVVKLGKDSNGHLSVTNVNCDAKVGDVQMNFYGGQSWIFKPFLKYYKGHVLAAIQANICPNVEDFIVKVESHLQALNVSIIVDSFLSLDLNLTSSPVIDSTSLNLPLKGQFYSIKTHKEPPFVAQPFTMPKQTDYMLSIGLSDFTANSASYAYYSDGQLMMYIDDKMIPPASPVHLNTSSMGPYIPQLPQMFPNLLMKLLVYARNCPMFSFQPGAVKLGLPLAIKAFAIQPNTSLTPLFKLHVVRVFSPKCFFTFVPYKKSIKAHAVFTQADNYSSRCLGKINSGRRMDFNFITAVKI
    

Molecular Weight46846.96 Da

Isoelectric Point (pI)8.88

Net Charge (pH 7.0)7.39

Net Charge (pH 7.4) 6.42

Charge Density (pH 7.0) 0.0173

GRAVY Index0.21

Hydrophobic Moment 0.61

Boman Index0.20

Instability Index34.74

Aliphatic Index 97.44

Aromaticity 0.1080

Extinction Coeff. Reduced 40340.00

Extinction Coeff. Oxidized 40715.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0240855 VERIFIED: NO

Provenance & Taxonomy

OrganismSphaeramia orbicularis [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria