Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length424 amino acids

Chemical FormulaC2107H3369N545O598S16

DescriptionStandard

        MFLWCVLVLLNLVSVATGTNAGVKVRLTQKGLEYGRQIGIASIQQKLRTIKVPDISGTEKVDPIGKVQYSFTGMQIVNLGLPKSALVLVPDTGVMLSIGNAYINLHGNWRVKYLRIIKDSGSFDLAVSELTISTTVAVMSDDTGRPTVSMTNCAATVGSVNVKFHGGASWLYNLFSSFINKALRNALQKQICPLVADSIGEFYNIGQHKEPPFSPTPFSLPSQDTDMLYIGVSAFTINSAGFVYNRAGALHLYITDDMIPSGSPIRLNTKTFGAFIPQIEKMYPGLMMKLLVETVKEPIVTFEPNNMTVQASSTVTAYAIHHTRRSVSTHIYVTELKLAGNIQTIILLNRINMSLAKSYVGPFQVTSLDNIFTIVLKFAVIPKVNARLQEGYPLPAIGKMQLVNSQLKVLKDYLLIGTDVQFTG
    

Molecular Weight46416.62 Da

Isoelectric Point (pI)9.40

Net Charge (pH 7.0)11.09

Net Charge (pH 7.4) 10.39

Charge Density (pH 7.0) 0.0262

GRAVY Index0.22

Hydrophobic Moment 0.72

Boman Index0.17

Instability Index32.45

Aliphatic Index 105.47

Aromaticity 0.0849

Extinction Coeff. Reduced 38850.00

Extinction Coeff. Oxidized 38975.00

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Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0022180 VERIFIED: NO

Provenance & Taxonomy

OrganismCyprinus carpio [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria