Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length512 amino acids

Chemical FormulaC2524H3988N634O739S28

DescriptionStandard

        MFKLQGIMLPSVMVVFAILSCTRAENPAVQVTLTDKWLQYGEDNHLRLLCVWSLDVSCVHASPKSVAVKHVGAGWIQDKLEHITFPDISGDVDILIGHVYYTLSGIRITKCDLPEPVLEFFQSTGLKTSIVGLNAALVGNWRTSFGIIHDSGSFDMAIFSVSLTSVVQLGRDPDGHLSITSIGCEPQVGNVAIQFHGGASFMFQPFVDHYKDKIVSVIQSNICPNVQTAIDDLESHLQAMSISYDVNEVLTVELPLTSPPVISGDDVNLGLKGEFYSIETHQEPPFVAQPFVLPKEPNYMMSVGLSEFMLNSASFGYFSAGNLQVLVNDSMIPPKSPIHLNTTSMGMFIPQLPKLYPDMLMNLQVYATEAPMLSLQMDVVEVGAQLGAKAFAIEPNGTQVPLFTLSVETRLSGKMWIVDEKLKANAMLDNITLTLASSEVGTFKMDALENVVKMGINLMGLPKLNALLGDGIVLPQMKQAQLVNPVLKLEKGFLVISSDTKIVQTNRNFSTL
    

Molecular Weight55936.29 Da

Isoelectric Point (pI)5.03

Net Charge (pH 7.0)-17.45

Net Charge (pH 7.4) -18.47

Charge Density (pH 7.0) -0.0341

GRAVY Index0.24

Hydrophobic Moment 0.57

Boman Index0.20

Instability Index38.04

Aliphatic Index 103.87

Aromaticity 0.0762

Extinction Coeff. Reduced 42400.00

Extinction Coeff. Oxidized 42775.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0294856 VERIFIED: NO

Provenance & Taxonomy

OrganismNothobranchius furzeri [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria

MethodQualitative functional evidence