MYP_068565
Basic Information
HG1
Antimicrobial
Antimicrobial Antibacterial
Antimicrobial Antibacterial Anti-Gram-negative
Antimicrobial Antibacterial Anti-Gram-positive
Antimicrobial Antifungal
Toxicity / Safety Blood cell toxicity Hemolysis Hemolytic
Venom / Toxin General toxin Toxic
Standard
19 amino acids
C94H152N28O22S
Standard
Sequence
KWLNALLHHGLNCAKGVLA
Physicochemical Analysis
2058.45 Da
9.31
1.92
1.60
0.1012
0.43
0.42
0.26
4.53
133.68
0.0526
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
798.49
-5.07
28.0
27.0
67.0
145.0
4.0
20.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0233975 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Halocidin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
APD analysis reveals that this sequence is 94.74% similar to Halocidin L: 26%, A: 16%, G=N=H=K: 11%. A lysine is added to the N-terminus of the wild type sequence and residues L3N4 were changed to KK. Warning: chain B sequence is the same as chain A. Chemical modification: there is an intermolecular S-S bond between the two chains
Bio-Activity Profile
Antimicrobial
Micrococcus luteus KCTC 9341
4 μg/mL
MIC
RECORD: Rec_0288644 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial
Bacillus subtilis KCTC 2213
RECORD: Rec_0292484 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Halocidin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Monomer: [P. grisea KACC40425
16-32 μg/mL
MIC
RECORD: Rec_0295586 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial
Human erythrocytes
100 μg/mL
Hemolysis
RECORD: Rec_0296972 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Halocidin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Dimer: [P. grisea KACC40425
16-32 μg/mL
MIC
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