Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length433 amino acids

Chemical FormulaC2194H3454N586O616S9

DescriptionStandard

        TDPGFVVRITQAGLDYAHQQGIAVLEKELVQLKLPDISGDFHIRRVGKVHYEISRLDLRSFHLPYSRISLVPKVGLQVSISNAFTEVDGNWRVKIHFIRDHGSFDLKVENIYIKINLKLGSDASGKPTIDTSDCSTHISQVRVRFSGKFGWLYNLFHSVIESRFRKALESKVCEKVGSSVHSELQPYIQTLPVTARIDAIAGIDYSLVAPPTATAQSLDVDLKDHDRMVYFGASSYFFNTAGFVYHAAGALVFEITDSMIPKSVDFHLNTSTFSAFVPQLEEMYPDMLMKLRLSAPSAPFLNIGPEGLSLKPVVDIQAYAILPNSSLAPLFLLGLVSNVSAVINVKSSHVVGNLKVGRMKLSLKHSDVGTFQVRTLQSIMNIFASSILLPRLNARLEEGFPLPLPDRIQLSNILVRFHQNFLLLGADVHYQPR
    

Molecular Weight48185.03 Da

Isoelectric Point (pI)8.84

Net Charge (pH 7.0)4.81

Net Charge (pH 7.4) 3.69

Charge Density (pH 7.0) 0.0111

GRAVY Index0.09

Hydrophobic Moment 0.74

Boman Index0.11

Instability Index36.76

Aliphatic Index 105.31

Aromaticity 0.0924

Extinction Coeff. Reduced 30370.00

Extinction Coeff. Oxidized 30495.00

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Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0296055 VERIFIED: NO

Provenance & Taxonomy

OrganismAramus guarauna (Limpkin) [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria