Peptide Database

Peptide NamePro-thyrotropin-releasing hormone

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Standard StatusStandard

Sequence Length218 amino acids

Chemical FormulaC1069H1673N345O348S2

DescriptionStandard

        QPEAAQQEAVTAAEHPGLDDFLRQVERLLFLRENIQRLQGDQGEHSASQIFQSDWLSKRQHPGKREEEEEEGVEEEEEEEGGAVGPHKRQHPGRREDEASWSVDVTQHKRQHPGRRSPWLAYAVPKRQHPGRRLADPKAQRSWEEEEEEEEREEDLMPEKRQHPGKRALGGPCGPQGAYGQAGLLLGLLDDLSRSQGAEEKRQHPGRRAAWVREPLEE
    

Molecular Weight24989.95 Da

Isoelectric Point (pI)5.27

Net Charge (pH 7.0)-13.27

Net Charge (pH 7.4) -14.08

Charge Density (pH 7.0) -0.0609

GRAVY Index-1.41

Hydrophobic Moment 0.93

Boman Index-0.33

Instability Index95.77

Aliphatic Index 54.68

Aromaticity 0.0459

Extinction Coeff. Reduced 30480.00

Extinction Coeff. Oxidized 30480.00

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Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0310108 VERIFIED: NO

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyTRH

Tax ID9606

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Other ModsPro62 Amidation; Pro92 Amidation; Gln111 Pyroglutamylation; Pro113 Amidation; Gln128 Pyroglutamylation; Pro130 Amidation; Pro164 Amidation; Gln203 Pyroglutamylation; Pro205 Amidation

Bio-Activity Profile

Function

Hormone Neuropeptide