Peptide Database

Peptide NameSarafotoxin SRTX-m3

Function Ontology

Cardiovascular ▸ Vascular tone modulation ▸ Vasoactive peptide

Cardiovascular ▸ Vascular tone modulation ▸ Vasoconstrictor activity

Venom / Toxin ▸ General toxin ▸ Toxin

Standard StatusStandard

Sequence Length24 amino acids

Chemical FormulaC123H178N30O41S5

DescriptionStandard

        CSCNDMNDKECVYFCHLDIIWDEP
    

Molecular Weight2893.23 Da

Isoelectric Point (pI)4.05

Net Charge (pH 7.0)-5.18

Net Charge (pH 7.4) -5.50

Charge Density (pH 7.0) -0.2160

GRAVY Index-0.33

Hydrophobic Moment 0.27

Boman Index0.01

Instability Index53.26

Aliphatic Index 60.83

Aromaticity 0.1250

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7240.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1144.76

LogP -9.30

H-bond Donors 41.0

H-bond Acceptors 42.0

Rotatable Bonds 91.0

Heavy Atoms 199.0

Ring Count 6.0

Amide Bonds 25.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0199268 VERIFIED: NO

Provenance & Taxonomy

OrganismAtractaspis engaddensis [Animal]; Atractaspis microlepidota microlepidota [Animal]

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide1-15; 3-11

Bio-Activity Profile

Function

Toxin

RECORD: Rec_0236992 VERIFIED: YES

Provenance & Taxonomy

OrganismAtractaspis microlepidota microlepidota [Animal]

FamilySarafotoxin-m3

Tax ID172021

Structure & Mods

Configdisulfide-constrained peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide1-15; 3-11

Bio-Activity Profile

Function

Vasoactive Vasoconstrictor

Half-LifeMammalian: 1.2 hour; Yeast: >20 hour; E. coli: >10 hour