MYP_068478
Basic Information
Ranacyclin-HB1
Antimicrobial
Antimicrobial Antibacterial
Antimicrobial Antibacterial Anti-Gram-positive
Antimicrobial Antifungal
Membrane / Ion-channel modulation Calcium channel modulation Calcium channel inhibitor
Toxicity / Safety Blood cell toxicity Hemolysis Hemolytic
Standard
20 amino acids
C100H150N26O25S2
Standard
Sequence
GAPKGCWTKSYPPQPCFGKK
Physicochemical Analysis
2180.55 Da
9.60
3.74
3.50
0.1868
-1.04
0.18
-0.09
42.01
5.00
0.1500
6990.00
7115.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
804.71
-7.52
28.0
31.0
64.0
153.0
8.0
20.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0052478 VERIFIED: YES
Provenance & Taxonomy
Pelophylax hubeiensis [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
6-16
Bio-Activity Profile
Antimicrobial Antioxidant
Candida albicans ATCC 10231, and C.glabrata 090902
150 μM
MIC
RECORD: Rec_0060191 VERIFIED: YES
Provenance & Taxonomy
Pelophylax hubeiensis [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antioxidant Anti-Gram-positive
Staphylococcus aureus
18.8 μM
MIC
RECORD: Rec_0077830 VERIFIED: YES
Provenance & Taxonomy
Pelophylax hubeiensis [Animal]
Ranacyclin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Candida glabrata 090902
RECORD: Rec_0088905 VERIFIED: YES
Provenance & Taxonomy
Pelophylax hubeiensis [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
6-16
Bio-Activity Profile
Antimicrobial Antioxidant
Staphylococcus aureus ATCC 25923
18.8 μM
MIC
RECORD: Rec_0159772 VERIFIED: YES
Provenance & Taxonomy
Pelophylax hubeiensis [Animal]
Ranacyclin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
human red blood cells
8.5 % hemolysis at 200 μM
Hemolysis
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