Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length279 amino acids

Chemical FormulaC1429H2303N375O413S8

DescriptionStandard

        MRTNILILLQFDFYINERRSINWILRKITSLFNGFVRTHLKNQICNKLQTLLADLNTQLKTLKSKVSEYAEIDYSLRSPVVFDNSIEMGLKGVFYNTQQRVEPPSSPPAFSLASQNTNMFYIAVSAFTINSAFMVLHRTNVFNIRITDDMVPSVSPIRLSTTTFGAFIPQISETHPDLKLELKVKTVKEPIIKFEPNHVILQLLSTVTAYDVQSGNTPTQLFVLNLESVASVQVSVEEGDLALDLTLEKIEGSMNGKPFKVQIKKKSLLKVCLKRNTNK
    

Molecular Weight31601.36 Da

Isoelectric Point (pI)9.41

Net Charge (pH 7.0)7.85

Net Charge (pH 7.4) 7.33

Charge Density (pH 7.0) 0.0281

GRAVY Index-0.05

Hydrophobic Moment 0.83

Boman Index0.05

Instability Index44.14

Aliphatic Index 103.33

Aromaticity 0.0824

Extinction Coeff. Reduced 14440.00

Extinction Coeff. Oxidized 14565.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0163571 VERIFIED: NO

Provenance & Taxonomy

OrganismCyprinus carpio [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria