Peptide Database

Peptide NameCryptdin-5

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Standard StatusStandard

Sequence Length36 amino acids

Chemical FormulaC186H303N57O48S6

DescriptionStandard

        LSKKLTCYCRKRGCNKRERVTGICRNLFFTYVFCCS
    

Molecular Weight4298.14 Da

Isoelectric Point (pI)9.70

Net Charge (pH 7.0)7.70

Net Charge (pH 7.4) 7.40

Charge Density (pH 7.0) 0.2138

GRAVY Index-0.22

Hydrophobic Moment 0.57

Boman Index-0.22

Instability Index26.05

Aliphatic Index 59.44

Aromaticity 0.1389

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1760.49

LogP -18.10

H-bond Donors 72.0

H-bond Acceptors 62.0

Rotatable Bonds 145.0

Heavy Atoms 297.0

Ring Count 5.0

Amide Bonds 37.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0097485 VERIFIED: YES

Provenance & Taxonomy

OrganismMus pahari [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)