Peptide Database

Peptide NameLL-37 (9-29)

Function Ontology

Anticancer

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antiviral

Antiviral ▸ Anti-HIV ▸ Anti-HIV-1

Antiviral ▸ Antiviral mechanism ▸ Viral entry inhibition

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length21 amino acids

Chemical FormulaC119H204N36O30

DescriptionStandard

        SKEKIGKEFKRIVQRIKDFLR
    

Molecular Weight2619.12 Da

Isoelectric Point (pI)10.55

Net Charge (pH 7.0)4.46

Net Charge (pH 7.4) 4.24

Charge Density (pH 7.0) 0.2125

GRAVY Index-1.00

Hydrophobic Moment 0.97

Boman Index-0.45

Instability Index7.30

Aliphatic Index 88.10

Aromaticity 0.0952

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1136.34

LogP -8.05

H-bond Donors 41.0

H-bond Acceptors 35.0

Rotatable Bonds 98.0

Heavy Atoms 185.0

Ring Count 2.0

Amide Bonds 21.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0378341 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyCathelicidin

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antiviral

TargetHIV

FIRST PREV 1 2 3

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