Peptide Database

Peptide NameType-A lantibiotic

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length110 amino acids

Chemical FormulaC559H889N149O174S5

DescriptionStandard

        MRYFQMAKQQMNLVEIEAMNSLQELTLEELDNVLGAGGGVIQTIVLSNQFYSDKTMVIVSHQLDIVNYVDSIIFVDKSSGDVIKDTHDNLIYRNQNYRKLFGLKEKVHND
    

Molecular Weight12641.26 Da

Isoelectric Point (pI)5.04

Net Charge (pH 7.0)-5.22

Net Charge (pH 7.4) -5.62

Charge Density (pH 7.0) -0.0475

GRAVY Index-0.23

Hydrophobic Moment 0.53

Boman Index0.03

Instability Index22.02

Aliphatic Index 102.64

Aromaticity 0.0818

Extinction Coeff. Reduced 7450.00

Extinction Coeff. Oxidized 7450.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 5304.81

LogP -49.77

H-bond Donors 178.0

H-bond Acceptors 177.0

Rotatable Bonds 438.0

Heavy Atoms 887.0

Ring Count 12.0

Amide Bonds 126.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0087979 VERIFIED: NO

Provenance & Taxonomy

OrganismStreptococcus sp. C150 [Bacterium]

FamilyLantibiotic

Tax ID435842

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Lantibiotic Non-hemolytic Non-ribosomal