Peptide Database

Peptide NameHepcidin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length179 amino acids

Chemical FormulaC852H1333N241O274S15

DescriptionStandard

        NVEQTNKDKKFLIPTAENFLHSPSQHPSESDASLKSSYCTVGAVSDEATAALVSINSSRFYTFNHQTGEEVKGADKSHQKSERIETLKQSNPPKMKTFSVAVAVAVVLAFICLQESSAVPVTEVQELEEPMSNEYQEMPVESWKMPYNNRHKRHSSPGGCRFCCNCCPNMSGCGVCCRF
    

Molecular Weight19817.12 Da

Isoelectric Point (pI)6.33

Net Charge (pH 7.0)-1.78

Net Charge (pH 7.4) -2.49

Charge Density (pH 7.0) -0.0100

GRAVY Index-0.50

Hydrophobic Moment 0.54

Boman Index-0.06

Instability Index70.22

Aliphatic Index 57.15

Aromaticity 0.0726

Extinction Coeff. Reduced 11460.00

Extinction Coeff. Oxidized 12085.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 8290.70

LogP -102.11

H-bond Donors 290.0

H-bond Acceptors 293.0

Rotatable Bonds 653.0

Heavy Atoms 1382.0

Ring Count 31.0

Amide Bonds 197.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0065469 VERIFIED: NO

Provenance & Taxonomy

OrganismDicentrarchus labrax [Animal]

FamilyHepcidin

Tax ID13489

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Non-hemolytic Non-ribosomal