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MYP_068353
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Basic Information
Cyclonellin
Anticancer
Antimicrobial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Standard
8 amino acids
C45H64N12O13
Standard
Sequence
ANPRYPYT
Physicochemical Analysis
981.06 Da
8.63
0.79
0.60
0.0992
-1.59
0.20
-0.25
-8.89
12.50
0.2500
2980.00
2980.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
415.12
-3.76
14.0
14.0
24.0
70.0
4.0
8.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0308598 VERIFIED: YES
Provenance & Taxonomy
Axinella carteri [Animal]
Structure & Mods
side-chain cyclized/stapled peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer
SK-HEP-1
50 μM
IC50
PMID29893558 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29893558/
RECORD: Rec_0308853 VERIFIED: YES
Provenance & Taxonomy
Axinella carteri [Animal]
Structure & Mods
side-chain cyclized/stapled peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer
MDA-MB-231
50 μM
IC50
PMID29893558 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29893558/
RECORD: Rec_0422838 VERIFIED: YES
Provenance & Taxonomy
Axinella carteri [Animal]
Structure & Mods
side-chain cyclized/stapled peptide [Cyclic]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
A549; HCT 116; K562; MDA-MB-231; SK-HEP-1; SNU-638
>50 μM
IC50
PaperDRAMP exact sequence record for Cyclonellin; anticancer IC50 reported for multiple tumor cell lines PMID29893558
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