Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length161 amino acids

Chemical FormulaC799H1282N222O236S15

DescriptionStandard

        MFLLSRSLSNQGAFFFFPLISTMPELRQKTCGLSSPKKSFTMKILLFFSTFLFFGVFIPPVGSGQTIGNSDSSSKIMCRRKLETLYSEARNSSTTSENTQYGTEENKTAKRKEHTVALNRRLACTMLGGQCKNKCGEKEFRIIYCERPTTLCCMRECDSKK
    

Molecular Weight18255.05 Da

Isoelectric Point (pI)9.50

Net Charge (pH 7.0)11.51

Net Charge (pH 7.4) 11.07

Charge Density (pH 7.0) 0.0715

GRAVY Index-0.35

Hydrophobic Moment 0.64

Boman Index-0.08

Instability Index57.98

Aliphatic Index 61.80

Aromaticity 0.0994

Extinction Coeff. Reduced 4470.00

Extinction Coeff. Oxidized 4970.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7470.70

LogP -83.56

H-bond Donors 274.0

H-bond Acceptors 264.0

Rotatable Bonds 622.0

Heavy Atoms 1272.0

Ring Count 23.0

Amide Bonds 172.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0335582 VERIFIED: NO

Provenance & Taxonomy

OrganismSus scrofa [Animal]

FamilyDefensin

Tax ID9823

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence