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MYP_068324
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Basic Information
[RLLR]5
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antifungal
Antiparasitic ▸ Antiprotozoal
Antiparasitic ▸ General antiparasitic ▸ Antiparasitic
Antiviral
Antiviral ▸ Anti-Herpesvirus ▸ Anti-HSV
Enzyme modulation ▸ Enzyme inhibition ▸ Binding inhibition
Standard
20 amino acids
C120H232N50O21
Standard
Sequence
RLLRRLLRRLLRRLLRRLLR
Physicochemical Analysis
2711.45 Da
12.00
9.76
9.56
0.4880
-0.35
1.10
-0.73
172.21
195.00
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1235.22
-7.30
51.0
31.0
99.0
191.0
0.0
19.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0344636 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antiviral Antifungal
Candida albicans
8 μg/mL
MIC
PMID14718539;10890923 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/14718539/
RECORD: Rec_0351978 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Protein-derived synthetic peptide
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antiviral Anti-HSV Binding inhibition
HSV-1 | NP-2/CD4/CCR5 cells
3.3 μM
IC50
Mammalian: 1 h; Yeast: 2 min; E. coli: 2 min
PaperApolipoprotein E-derived antimicrobial peptide analogues with altered membrane affinity and increased potency and breadth of activity. | Kelly BA, Neil SJ, McKnight A, Santos JM, Sinnis P, Jack ER, Middleton DA, Dobson CB. | FEBS J. 2007 Sep;274(17):4511-25. | DOI:10.1111/j.1742-4658.2007.05981.x | PMID:17681018 PMID17681018 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17681018/
RECORD: Rec_0356906 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antiviral Antifungal
Staphylococcus aureus ATCC 6538P
16 μM
IC50
PMID14718539;10890923 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/14718539/
RECORD: Rec_0364297 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antiviral Antifungal
Staphylococcus aureus ATCC 15752
64 μg/mL
MIC
PMID14718539;10890923 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/14718539/
RECORD: Rec_0395394 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antiviral Antifungal
Staphylococcus aureus ATCC 15752
4 μg/mL
MIC
PMID14718539;10890923 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/14718539/
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