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MYP_068296
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Basic Information
Vaby A
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Antiviral
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
29 amino acids
C115H183N35O40S6
Standard
Sequence
GLPVCGETCAGGTCNTPGCSCSWPICTRN
Physicochemical Analysis
2888.28 Da
5.96
-0.30
-0.59
-0.0102
0.08
0.26
0.14
45.48
40.34
0.0345
5500.00
5875.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1174.30
-18.89
46.0
46.0
84.0
196.0
5.0
30.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0391477 VERIFIED: YES
Provenance & Taxonomy
Viola abyssinica [Plant]
Cyclotide
Structure & Mods
Backbone-cyclized cyclotide scaffold with cystine-knot family annotation [Cyclic]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PMID21434649 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21434649/
RECORD: Rec_0414676 VERIFIED: YES
Provenance & Taxonomy
Viola abyssinica [Plant]
Cyclotide
Structure & Mods
head-to-tail cyclic peptide scaffold [Cyclic]
canonical L-amino-acid peptide [L]
Cysteine-rich scaffold consistent with multiple disulfide bonds in the annotated family
Bio-Activity Profile
Antimicrobial Antibacterial Anticancer Cytotoxic Anti-Gram-negative
Escherichia coli
32.5 μM
MIC
PMID21434649;20558470 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21434649/
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