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MYP_068296
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Basic Information
Vaby A
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Antiviral
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
29 amino acids
C115H183N35O40S6
Standard
Sequence
GLPVCGETCAGGTCNTPGCSCSWPICTRN
Physicochemical Analysis
2888.28 Da
5.96
-0.30
-0.59
-0.0102
0.08
0.26
0.14
45.48
40.34
0.0345
5500.00
5875.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1174.30
-18.89
46.0
46.0
84.0
196.0
5.0
30.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0057153 VERIFIED: YES
Provenance & Taxonomy
Viola abyssinica [Plant]; Insecta [Animal]
33090; 50557
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PMID21867685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21867685/
RECORD: Rec_0066422 VERIFIED: YES
Provenance & Taxonomy
Ethiopian highlands [Plant]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Anticancer
PaperCyclotides from an extreme habitat: characterization of cyclic peptides from Viola abyssinica of the Ethiopian highlands
RECORD: Rec_0097493 VERIFIED: NO
Provenance & Taxonomy
Viola abyssinica [Plant]; Insecta [Animal]
33090; 50557
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Anticancer
PaperAPD2: the updated antimicrobial peptide database and its application in peptide design PMID18957441 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18957441/
RECORD: Rec_0099963 VERIFIED: YES
Provenance & Taxonomy
Viola abyssinica [Plant]
Cyclotide
Structure & Mods
head-to-tail cyclic peptide scaffold [Cyclic]
canonical L-amino-acid peptide [L]
Cysteine-rich scaffold consistent with multiple disulfide bonds in the annotated family
Bio-Activity Profile
Antimicrobial Antibacterial Anticancer Cytotoxic Anti-Gram-negative
Salmonella enterica serovar Typhimurium
90 μM
MIC
PMID21434649;20558470 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21434649/
RECORD: Rec_0143487 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer
PaperAPD2: the updated antimicrobial peptide database and its application in peptide design PMID18957441 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18957441/
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